Incidence of dementia in the German Heinz Nixdorf Recall study over 20 years.

ABSTRACT:

Introduction

The aim of the study was to estimate the population-based dementia incidence in Germany over a period of two decades.

Methods

We analyzed data from 4814 participants of the population-based Heinz Nixdorf Recall study (49.8% men, 45-75 years at baseline period 2000-2003), who have been monitored for the occurrence of cognitive decline and dementia. We calculated the cumulative incidence of dementia and its major subtypes and the incidence rate per 1000 person-years over two decades.

Results

During a median follow-up of 18.2 (Q1-Q3: 11.3-20.6) years, a total of 298 participants (6.2%) developed dementia (22.1% Alzheimer´s disease, 23.5% vascular dementia, 15.1% mixed dementia, 9.1% other dementia, 30.2% unspecified). The overall incidence rate was 3.9 per 1

SUBMITTER: Schramm S 

PROVIDER: S-EPMC11736620 | biostudies-literature | 2025 Jan-Mar

REPOSITORIES: biostudies-literature