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Conservation anchors in the vertebrate genome.


ABSTRACT: Genomic segments that do not code for proteins yet show high conservation among vertebrates have recently been identified by various computational methodologies. We refer to them as ANCORs (ancestral non-coding conserved regions). The frequency of individual ANCORs within the genome, along with their (correlated) inter-species identity scores, helps in assessing the probability that they function in transcription regulation or RNA coding.

SUBMITTER: Aloni R 

PROVIDER: S-EPMC1175977 | biostudies-literature | 2005

REPOSITORIES: biostudies-literature

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Conservation anchors in the vertebrate genome.

Aloni Ronny R   Lancet Doron D  

Genome biology 20050629 7


Genomic segments that do not code for proteins yet show high conservation among vertebrates have recently been identified by various computational methodologies. We refer to them as ANCORs (ancestral non-coding conserved regions). The frequency of individual ANCORs within the genome, along with their (correlated) inter-species identity scores, helps in assessing the probability that they function in transcription regulation or RNA coding. ...[more]

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