Ratiometric discrimination of Th⁴⁺ ions by a fluorogenic quinoline appended phenanthridine sensor and its applications.

ABSTRACT: A new phenanthridine appended quinoline-based chemoreceptor 5-(5-(quinolin-8-yl)thiophen-2-yl)-tetrahydrodibenzo[a,i]phenanthridine (PHQBA) was successfully synthesized and characterized by ¹H, ¹³C, and HRMS spectral analyses. The promising chelation-induced process in PHQBA was accelerated by Th⁴⁺ ions, which impart robust ratiometric green fluorescence at 515 nm. The host-guest complex formed in a 1 : 1 binding stoichiometry between Th⁴⁺ ions and PHQBA was demonstrated by Jobs plot experiments. The Benesi-Hildebrand (BH) plot was employed to compute the binding constant for the complexation of PHQBA + Th⁴⁺, which was determined to be 3.77 × 10⁵ M^-1. To comprehend the detection mechanism of PHQBA, DFT, and TDDFT,

SUBMITTER: Manoj Kumar S 

PROVIDER: S-EPMC11808482 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature