HIV Exposure and Neonatal Sepsis: A Descriptive Etiological Study.

ABSTRACT:

Background

Low- and middle-income countries lack data on culture-confirmed sepsis in HIV-exposed infants, despite the reported heightened risk of infectious morbidity. This study describes culture-confirmed sepsis and antibiotic resistance patterns among HIV-exposed children in a large etiological cohort study in Kampala, Uganda.

Methods

This was a prospective birth cohort study based at 2 Ugandan sites, as part of the Progressing Group B Streptococcal Vaccines (PROGRESS) study. Any infant with risk factors, signs, or symptoms of infection presenting before 3 months of age had a blood culture and nasopharyngeal swab taken to determine the etiology of neonatal and young infant sepsis.

Results

Among 4492 blood cultures, 460 were obtained from HIV-exposed infants. Nine i

SUBMITTER: Atuhaire P 

PROVIDER: S-EPMC11891132 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature