The intraoperative SEEG and ¹⁸FDG-PET tailored temporal lobe resection (iSP-TR) for the tissue-spearing surgical treatment of drug-resistant mesial temporal lobe epilepsy: how we do it.

ABSTRACT:

Background

For drug-resistant mesial temporal lobe epilepsy (MTLE), surgery is recommended. There is no evidence of a seizure outcome advantage of temporal lobectomy over other strategies despite the high risks of this surgical procedure.

Methods

We describe a Temporal Resection guided by intraoperative stereo-electroencephalography (iSEEG) and the ¹⁸FluoroDeoxyGlucose PET (¹⁸FDG PET) (iSP-TR) to treat lesional MTLE. We avoided functional cortical areas using navigated Transcranial Magnetic Stimulation (nTMS).

Conclusion

iSP-TR allows for a spare brain parenchyma compared to temporal lobectomy without compromising seizure outcomes.

SUBMITTER: Battista F 

PROVIDER: S-EPMC11922984 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature