Education Levels and Poststroke Cognitive Trajectories.

ABSTRACT:

Importance

Acute stroke is associated with accelerated, years-long cognitive decline. Whether education levels are associated with faster cognitive decline after stroke is unclear.

Objective

To evaluate the association of education level with poststroke cognitive decline and to determine whether age at stroke modifies the association.

Design, setting, and participants

Individual participant data meta-analysis of 4 US cohort studies (January 1971 to December 2019). Analysis began August 2022 and was completed in January 2024.

Exposures

Education level (less than high school, completed high school, some college, and college graduate).

Main outcomes and measures

Harmonized cognitive outcomes were global cognition (primary outcome), memory, and executive fun

SUBMITTER: Springer MV 

PROVIDER: S-EPMC11947833 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature