Accurate and precise in vivo liver 3D T₁ mapping at 3T.

ABSTRACT:

Purpose

To develop an accurate and precise liver 3D T1$$ {T}_1 $$ mapping method using only scanner-agnostic sequences.

Methods

While the spoiled gradient-recalled echo sequence is widely available on clinical scanners, variable flip angle T1$$ {T}_1 $$ mapping methods based on this sequence provide biased T1$$ {T}_1 $$ estimates, with the largest systematic error arising from B1+$$ {B}_1^{+} $$ inhomogeneities. To correct for this, the flip angle was mapped using a 2D gradient-echo double-angle method approach. To correct for the confounding effect of fat on liver T1$$ {T}_1 $$ and B1+$$ {B}_1^{+} $$ , Dixon and fat saturation techniques were used in combination with the variable flip angle and the B1+$$ {B}_1^{+} $$ map acquisitions, respectively. The T1$$ {T}_1 $$ and B1+

SUBMITTER: Belsley G 

PROVIDER: S-EPMC11971508 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature