Fox Insight: Most Bothersome Symptoms in Early-Stage Parkinson's Disease.

ABSTRACT:

Background

Limited evidence exists regarding the meaningfulness of symptoms experienced in early Parkinson's disease (PD).

Objectives

To identify the most bothersome symptoms experienced by people with early PD, leveraging data from the Parkinson's Disease Patient Report of Problems (PD-PROP) questionnaire within the Fox Insight Study.

Methods

Individuals with a self-reported diagnosis of PD completed the PD-PROP questionnaire, reporting up to five most bothersome symptoms. Symptom types and frequencies were derived through a combination of human expertise and machine learning.

Results

Participants (N = 8536) were 0.9 years since diagnosis, predominantly white (96%), male (53.3%), and with an average age of 64.6 years. Top most bothersome motor symptoms were tr

SUBMITTER: Lerner A 

PROVIDER: S-EPMC11998684 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature