Charting the Pathways of Cardiometabolic Multimorbidity: A Systematic Review of Clinical Trajectories.

ABSTRACT: Background: Managing multimorbidity is a major challenge for healthcare systems. Cardiometabolic multimorbidity (CMM) is highly prevalent and linked to increased disease burden, functional decline, and mortality. While most studies focus on cross-sectional analyses, longitudinal approaches are essential for understanding disease progression and identifying patient groups who may benefit from targeted interventions. Objectives: This systematic review synthesises evidence from longitudinal studies on the incidence and progression of CMM, exploring transitions between multimorbidity clusters and their clinical implications. Methods: A systematic search was conducted in MEDLINE and EMBASE following PRISMA guidelines. Studies were included if they employed longitudinal desi

SUBMITTER: Ioakeim-Skoufa I 

PROVIDER: S-EPMC12028097 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature