Validity and contributions to pain from the central aspects of pain questionnaire in rheumatoid arthritis.

ABSTRACT:

Introduction

The central nervous system (CNS) contributes to pain perception across musculoskeletal conditions. The central aspects of pain (CAP) questionnaire captures a single score associated with quantitative sensory testing (QST) evidence of CNS dysfunction validated in knee osteoarthritis.

Objectives

Given the different pathophysiology of rheumatoid arthritis (RA), an inflammatory polyarthritis, this cross-sectional study assessed CAP's psychometric properties and its association with pain in RA.

Methods

Adults with RA were recruited from Nottinghamshire, London, and Cardiff. Participants completed CAP and reported pain using a numerical rating scale. A subgroup underwent additional assessments, including quantitative sensory testing (QST; Pressure Pain detectio

SUBMITTER: Smith SL 

PROVIDER: S-EPMC12185087 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature