Mesoscopic whole-brain T₂*-weighted and associated quantitative MRI in healthy humans at 10.5 T.

ABSTRACT:

Purpose

To demonstrate the feasibility and performance of mesoscopic whole brain T₂*-weighted (T₂*w) MRI at 10.5 T by combining a motion-robust multi-echo gradient-echo (GRE) method with high-density RF receive arrays.

Methods

Multi-echo GRE data were collected in healthy adults at isotropic 0.5 mm resolution using a custom-built 16-channel transmit/80-channel receive (16Tx/80Rx) RF coil. Whole brain images were reconstructed with navigator-guided joint motion and field correction and were used for quantitative R ₂* and susceptibility (χ) mapping. Intrinsic signal-to-noise ratio (iSNR) and quantification precision for R ₂* and χ were also estimated. The results were compared with those obtained in the sa

SUBMITTER: Liu J 

PROVIDER: S-EPMC12190817 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature