Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral Deep Brain Stimulation and Probabilistic Lesion Mapping.

ABSTRACT:

Background

The efficacy and adverse events (AEs) of bilateral magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomies for essential tremor (ET) have not been compared to those of deep brain stimulation (DBS). Furthermore, it is uncertain whether second-side thalamotomies can be positioned differently from the first without compromising effectiveness.

Objective

We aimed to indirectly compare bilateral MRgFUS and DBS, while identifying optimal lesion/stimulation locations.

Methods

We retrospectively examined 41 ET patients who received either bilateral thalamic DBS (n = 22) or MRgFUS (n = 19) surgery. The primary outcome was the comparison of modalities for change in Clinical Rating Scale for Tremor (CRST) from baseline to post second surgery. We characteriz

SUBMITTER: Sarica C 

PROVIDER: S-EPMC12273620 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature