Carbapenemases producing gram-negative bacteria surveillance in Latin America and the caribbean: a retrospective observational study from 2015 to 2020.

ABSTRACT:

Background

The rise of multidrug-resistant (MDR) bacteria represents a public health threat, with carbapenem resistance exacerbating this challenge. This study investigates carbapenemase-producing bacteria (CPB) across the Latin America and the Caribbean (LAC) region.

Methods

A retrospective observational study was conducted across 12 LAC countries from 2015 to 2020. A total of 58,909 isolates were analyzed utilizing polymerase chain reaction (PCR) to detect key carbapenemases in Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter baumannii complex (ABC).

Findings

47,804/58,909 (81.14%) carbapenemases were identified, with Brazil accounting for 73% of these. The majority were reported in carbapenem-resistant Enterobacterales-CRE (65.33%; 31,230/4

SUBMITTER: Pillonetto M 

PROVIDER: S-EPMC12281157 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature