Virulence traits and bacterial interactions within the complex microbial population in urinary double-J catheters.

ABSTRACT: Indwelling devices, such as double-J stents, are commonly used in urological surgery and are often associated with a high risk of urinary tract infections (UTIs) due to biofilm-related complications. In this study, we characterized 27 clinical bacterial isolates from double-J catheters, including Staphylococcus spp., Enterococcus faecalis, Klebsiella pneumoniae, Escherichia coli, and Bacillus spp., to investigate their pathogenic potential. Our findings revealed that strong biofilm producers (E. coli, S. aureus, and B. subtilis) exhibited robust extracellular matrix synthesis. Notably, multidrug resistance was observed in E. coli, K. pneumoniae, and E. faecalis. Mixed-culture experiments demonstrated that Bacillus spp. enhanced the bi

SUBMITTER: Farizano JV 

PROVIDER: S-EPMC12286952 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature