A Halophilic Bacterium for Bioremediation of Saline-Alkali Land: The Triadic and Synergetic Response Mechanism of <i>Oceanobacillus picturae</i> DY09 to Salt Stress.

ABSTRACT: The strain of Oceanobacillus picturae DY09, as a typical halophilic microorganism, possesses distinctive salt adaptation mechanisms that hold significant application value in the fields of agriculture, industry, and biomedicine. To deeply analyze the salt-tolerance molecular mechanism of this strain, this research disclosed its salt-tolerance strategies under diverse salt concentrations through transcriptomics. In a low-salt environment, the DY09 strain adopted a "metabolic simplification" strategy, significantly reducing the metabolic load by promoting lysine degradation and inhibiting the biosynthesis of branched-chain amino acids and glycine betaine (GB) but upregulating the expression of the GB transporter gene betH and preferentially utilizing exogenous GB to maintain ba

SUBMITTER: Nie T 

PROVIDER: S-EPMC12297972 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature