<i>Moesziomyces antarcticus MMF1</i> Has a Role in the Secretion of Mannosylerythritol Lipids.

ABSTRACT: Mannosyl erythritol lipids (MELs) are glycolipid biosurfactants produced by Ustilaginomycete yeasts. The MEL biosynthetic pathway has been characterized in Ustilago maydis where a putative transporter encoded by MMF1 is required for the secretion of the glycolipid surfactant to the extracellular space. The anamorphic yeast Moesziomyces antarcticus is a prolific producer of MELs, but the mechanism of MEL secretion is less well characterized than in U. maydis. Homologous recombination was employed to generate a disruption of the MMF1 gene in M. antarcticus JCM10317. This mutation did not prevent the intracellular accumulation of MEL species but did result in significantly reduced secretion of the conventional MEL-A, MEL-B and MEL-C species det

SUBMITTER: Xu Y 

PROVIDER: S-EPMC12299085 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature