Longitudinal bone loss in the paretic leg and its contributing factors in individuals with chronic stroke: a 2-year prospective cohort study.

ABSTRACT: Post-stroke fracture risk necessitates investigation of bone properties and contributing factors. The decline in paretic tibia failure load post-stroke was attributed to decreased trabecular bone density and thickness at 2-year follow-up. Less decline in bone strength was associated with better leg blood flow, walking speed, strength, and activity at baseline.

Purpose

To delineate long-term changes in distal tibia bone properties after stroke and identify their associated factors.

Methods

High-resolution peripheral quantitative computed tomography (HR-pQCT) scans of the bilateral distal tibia were performed in 46 chronic stroke participants (age, 60.4 ± 7.8 years; post-stroke onset, 6.3 ± 4.2 years) and 45 controls (age, 57.7 ± 6.3 years) at baseline and 2 years later. We mea

SUBMITTER: Ouyang H 

PROVIDER: S-EPMC12325440 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature