Metal-organic framework-injectable hydrogel hybrid scaffolds promote accelerated angiogenesis for <i>in vivo</i> tissue engineering.

ABSTRACT: The application of nanoscale metal-organic frameworks (MOFs) in tissue engineering is receiving increased attention. As three-dimensional scaffolding materials that provide an appropriate extracellular microenvironment supporting the survival, proliferation, and organization of cells play a key role in vivo tissue engineering, hybridization of nanoscale MOFs with bulk hydrogels has led to the development of nanoscale MOF-combined hydrogels. However, development of nanoscale MOF-combined hydrogel scaffolds remains challenging. Generally, since the gelation properties of injectable hydrogels are delicate, the sol-gel transition behavior could be lost due to the influence of additives. To date, little progress has been made in the development of nanoscale MOF-combined injectable hydrog

SUBMITTER: Shahidul Islam S 

PROVIDER: S-EPMC12412208 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature