Systematic Review Suggests Nutraceuticals Containing Vitamin B2 Could Provide an Alternative Treatment for Paediatric Migraines.

ABSTRACT:

Aim

The aim of this review is to systematically summarise the evidence on the effectiveness of riboflavin (vitamin B2) or supplements containing riboflavin in preventing paediatric migraines.

Methods

This systematic review followed the Joanna Briggs Institute methodology and is reported to adhere to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched multiple electronic databases on 25 October 2023 to identify potentially relevant studies. Studies were screened, critically appraised and data extracted by two reviewers. Data underwent a narrative synthesis using vote counting based on direction of effect and was presented using harvest plots.

Results

Seventeen studies of varying quality were included in the review. Riboflavin

SUBMITTER: Martello E 

PROVIDER: S-EPMC12420874 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature