Green Co-Extractant-Assisted Supercritical CO₂ Extraction of Xanthones from Mangosteen Pericarp Using Tricaprylin and Tricaprin Mixtures.

ABSTRACT: Xanthones from mangosteen pericarp (MP) are bioactive compounds with promising pharmaceutical and nutraceutical applications. However, their efficient and selective extraction using environmentally friendly solvents remains a challenge. This study aimed to evaluate tricaprylin (C8) and tricaprin (C10) as novel green co-extractants in supercritical carbon dioxide (scCO₂) extraction for the recovery of xanthones from MP, using a mass ratio of C8:C10 = 0.64:0.36, hereafter referred to as C8/C10, and to model extraction kinetics for process design and scale-up. Extraction performance was investigated using different C8/C10-MP mass ratios and scCO₂ conditions at temperatures of 60 °C and 70 °C and pressures of 250 bar, 350 bar, and 450 bar. A pseudo-first-order kinetic mod

SUBMITTER: Liu H 

PROVIDER: S-EPMC12428359 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature