Dataset Information

Integrative network pharmacology, metabolomics and gut flora studies reveal mechanisms of action of <i>Rhododendron molle</i> (Blume) G. Don to ameliorate liver injury.

ABSTRACT:

Background

Liver injury (LI) is responsible for a significant number of fatalities each year. In the context of Mongolian medicine, Rhododendron molle (Blume) G. Don (RM) is utilized for its properties to treatment of hepatic disorders. However, the underlying mechanisms of its action remain poorly understood.

Objectives

Clarifying the process through which RM enhances LI.

Methods

The chemical constituents were subjected to analysis, and network pharmacology alongside molecular docking studies were conducted. Additionally, ELISA, staining techniques, metabolomic analyses, and 16S rDNA sequencing were performed.