Molecular characterization of carbapenem-resistant and carbapenem-sensitive <i>Acinetobacter baumannii</i> isolates from an intensive care unit in Ningbo, China.

ABSTRACT:

Objective

This study aims to examine the variations in resistance genes, virulence genes, and drug susceptibility between carbapenem-resistant and carbapenem-susceptible Acinetobacter baumannii (CR-AB and CS-AB). Additionally, it seeks to assess the influence of efflux pump inhibitors on drug susceptibility, in order to provide new antimicrobial treatment strategies for CR-AB infections in the intensive care unit (ICU).

Methods

A retrospective study was undertaken involving 39 A. baumannii (A. baumannii) strains isolated from the ICU of Li Huili Hospital, affiliated with Ningbo University, during the period from January to December 2023. Of these strains, 18 were classified as CR-AB and 21 as CS-AB. The minimum inhibitory concentrations (MICs) of commonl

SUBMITTER: Chen X 

PROVIDER: S-EPMC12440978 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature