Global, regional, and national burden of atrial fibrillation and flutter associated with metabolic risk factors, 1990-2021.

ABSTRACT:

Objectives

Atrial fibrillation/flutter (AF/AFL) is increasingly correlated with metabolic risk factors. This study analyzed mortality, disability-adjusted life years (DALYs), annual percentage changes (APCs), and estimated annual percentage changes (EAPCs), stratified by age, sex, Socio-demographic Index (SDI), and region, to evaluate the global burden of AF/AFL linked to metabolic risk factors.

Methods

Data on prevalence, incidence, mortality, DALYs, and age-standardized rates (ASRs) for AF/AFL associated with metabolic risk factors were extracted from the Global Burden of Disease (GBD) 2021 study. EAPCs were used to assess temporal trends in ASRs.

Results

In 2021, metabolic risk factors were correlated with approximately 117,012 deaths and 2,881,800 DALYs globally d

SUBMITTER: Wang L 

PROVIDER: S-EPMC12450952 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature