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ABSTRACT: Background
To bridge the gap between clinical guidelines and suboptimal stroke management in rural settings, we conducted an implementation trial using evidence-based, mobile health-enabled strategies to empower primary care providers in rural China. The system-integrated and digital technology-enabled model of care (SINEMA) model was shown to significantly reduce blood pressure and mortality among people with stroke in rural China.Objective
This study aimed to evaluate the cost-effectiveness of the SINEMA intervention within both the active trial and the post-trial observational periods and its budget impact for potential nationwide scalability.Methods
In the cluster-randomized implementation trial (the SINEMA trial), 50 villages were randomized to either a 1-year
SUBMITTER: Yang B
PROVIDER: S-EPMC12464504 | biostudies-literature | 2025 Sep
REPOSITORIES: biostudies-literature