Functional Annotation and Comparative Analysis of Cytochrome P450 Protein Family Genes in Nine Chironomidae Species.

ABSTRACT: Cytochrome P450 monooxygenases (P450s) are one of the most widespread enzyme superfamilies in the biological world. In insects, P450 proteins play a crucial role in the synthesis of endogenous substances and the metabolism of xenobiotics. To date, extensive research has been conducted on P450 gene-mediated detoxification and metabolism across multiple insect species. While Chironomidae species-dominant benthic organisms inhabiting diverse ecological niches and playing critical ecological roles-remain largely uncharacterized in terms of P450 protein annotation, with the exception of a single study on Propsilocerus akamusi. In this study, we expanded the annotation scope by identifying the P450 protein genes in eight additional Chironomidae species. A total of 577 P450 protein genes w

SUBMITTER: Liu W 

PROVIDER: S-EPMC12467003 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature