Antimicrobial mechanical and molecular docking analysis of dental composite resin incorporating green synthesized titanium dioxide nanoparticles from Vitis vinifera extract.

ABSTRACT: Dental composites are widely used restorative materials but secondary caries to the restored tooth, polymerization shrinkage, and mechanical failure, limiting their longevity. Incorporating nanoparticles synthesized via eco-friendly methods offers a promising strategy to enhance composite performance. This study introduces a novel, eco-friendly strategy to enhance dental composite resins by incorporating TiO₂-NPs synthesized using Vitis vinifera extract. This study uniquely employs Vitis vinifera, rich in flavonoids and phenolics, as a reducing and capping agent, and for the first time integrates molecular docking analysis to explore the mechanistic antimicrobial interaction between TiO₂-NPs and Streptococcus mutans glucosyltransferase. The research evaluates the impact of these green-synt

SUBMITTER: Abozaid D 

PROVIDER: S-EPMC12508154 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature