Association of triglyceride-glucose index and its related parameters with the risk of stroke: a meta-analysis.

ABSTRACT:

Objective

The triglyceride-glucose (TyG) index and its related parameters are biomarkers of insulin resistance (IR) and maybe of great significance for predicting the occurrence of stroke. This systematic review and meta-analysis aimed to summarize the relationship between TyG and its related parameters with the risks of stroke.

Methods

By searching the Cochrane Library, Embase, and PubMed databases, we obtained prospective cohort studies that reported the hazard ratios (HRs) and their 95% confidence intervals (CIs) for the association between the TyG index and its related parameters (TyG-BMI, TyG-WC, TyG-WHtR) and stroke incidence. The results were combined using a random-effects model.

Results

This meta-analysis included 21 prospective cohort studies with a total of

SUBMITTER: Yang Y 

PROVIDER: S-EPMC12509345 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature