Impact of a food supplement containing <i>Citrus limon</i> L. Osbeck and <i>Vitis vinifera</i> L. extracts, hesperidin and chromium in combination with an isocaloric diet on glucose and lipid metabolism in subjects with impaired fasting blood glucose: a single-center, controlled, randomized, parallel-arm, double-blind clinical trial.

ABSTRACT:

Introduction

Impaired fasting glycemia (IFG) puts carriers at a significantly higher risk of developing type 2 diabetes and cardiovascular disease. Lifestyle changes, such as increased physical activity and a healthy diet rich in fiber and low in sugar, can often reverse prediabetes and significantly reduce the risk of progressing to type 2 diabetes metabolic disorders, especially diabetes (1).

Methods

This randomized clinical trial aims to evaluate the efficacy and tolerability of a food supplement (FS) containing Citrus limon L. Osbeck and Vitis vinifera L. extracts, hesperidin from Citrus sinensis L. Osbeck, and chromium, in individuals with impaired fasting blood glucose , with the final goal of investigating whether the use of a combination of ingre

SUBMITTER: Di Minno A 

PROVIDER: S-EPMC12558782 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature