ST8SIA6-AS1 serves as a prognostic biomarker in cancer and exhibits oncogenic properties in prostate cancer.

ABSTRACT:

Background

The prognostic significance of long non-coding RNA ST8SIA6-AS1 remains ambiguous, and its biological role in prostate cancer (PCa) has not been thoroughly investigated. This study seeks to conduct a comprehensive meta-analysis to assess the clinical relevance of ST8SIA6-AS1 across different malignancies, with a particular emphasis on elucidating its functions in the advancement of PCa.

Methods

Systematic searches were conducted in the PubMed, Embase, and Web of Science databases to select studies that met the criteria. Data, including hazard ratios (HR) with 95% confidence intervals (95% CI) and clinical pathological parameters, were collected. Subgroup analyses were performed based on sample size and tumor type. The expression profile analysis of PCa tissues was

SUBMITTER: Wen Y 

PROVIDER: S-EPMC12634032 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature