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Accuracy of computed tomography perfusion-defined ischemic core and follow-up infarction after basilar artery thrombectomy.


ABSTRACT:

Purpose

Accurate identification of computed tomography (CT) perfusion ischemic core in patients with basilar artery occlusion (BAO) on admission remains challenging despite its critical role in prognostic prediction and treatment decision-making. We aimed to define the optimal threshold for identifying the ischemic core by assessing agreement in lesion extent and spatial distribution using Syngo.via.

Methods

We retrospectively analyzed 91 patients with BAO who achieved successful recanalization after endovascular thrombectomy at our center. The ischemic core was estimated using the following thresholds: cerebral blood flow (CBF) < 10 or 15 mL/100 g/min by Syngo.via, cerebral blood volume < 1.2 mL/100 mL by Syngo.via, and time to maximum > 10 s by RAPID. The Posterior Circula

SUBMITTER: Chen P 

PROVIDER: S-EPMC12641287 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature