Twenty-year Patient-reported Outcomes After Surgery, Radiotherapy, or Brachytherapy for Localized Prostate Cancer.

ABSTRACT:

Background and objective

Our objective was to compare the impact of open radical prostatectomy (RP), external beam radiotherapy (EBRT), and brachytherapy in patients with localized prostate cancer via patient-reported outcome measures up to 20 yr after treatment.

Methods

This was a prospective observational study (ClinicalTrials.gov NCT01492751) of men with localized prostate cancer (clinical stage T1-T2, low or intermediate risk). The Expanded Prostate Cancer Index Composite (EPIC-26) and Short Form-36 (SF-36) questionnaires were centrally administered via telephone interviews before treatment and then annually after treatment. Generalized estimating equation models were constructed with propensity score-based weights.

Key findings and limitations

The RP group report

SUBMITTER: Zamora V 

PROVIDER: S-EPMC12648591 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature