Phylogenomics and Antimicrobial Resistance of Clinical <i>Bacteroides</i> Isolates from a Tertiary Hospital in Southern Thailand.

ABSTRACT: Background/Objectives: Bacteroides species are key members of the human gut microbiota but can act as opportunistic pathogens. This study investigated the genomic features of clinical Bacteroides isolates from southern Thailand. Methods: Sixteen isolates were collected from body fluids, tissues, and pus at Songklanagarind Hospital (2022-2024). Whole-genome sequencing was performed on the BGI platform, followed by genome assembly, annotation, average nucleotide identity (ANI), pairwise single-nucleotide polymorphism (SNP) analysis, antimicrobial resistance (AMR) gene profiling, plasmid prediction, virulence screening, and phylogenetic analysis. Results: ANI and SNP analysis revealed two clusters: one comprising B. ovatus, B. intestinigallinarum</

SUBMITTER: Yingkajorn M 

PROVIDER: S-EPMC12649151 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature