Higher adherence to (poly)phenol-rich diet is associated with lower CVD risk in the TwinsUK cohort.

ABSTRACT:

Background

Previous studies have reported inverse associations between total (poly)phenol intake or specific subclasses of (poly)phenols, estimated from dietary questionnaires, and cardiovascular disease (CVD) risk. However, no studies have examined (poly)phenol-rich dietary patterns and their corresponding urinary metabolite profiles in relation to CVD risk. This study investigated the associations between a (poly)phenol-rich dietary score (PPS-D), its urinary metabolic signature (PPS-M), and longitudinal CVD risk in the TwinsUK cohort.

Methods

We included 3110 participants (followed up for 11.20 ± 7.03 years) from TwinsUK who completed the EPIC-Norfolk Food Frequency Questionnaire with longitudinal data. A subset of 200 participants provided spot urine samples, in which 11

SUBMITTER: Li Y 

PROVIDER: S-EPMC12659045 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature