A TIR-NLR gene from Arabidopsis Pla-1 confers resistance to geminivirus infection.

ABSTRACT: Geminiviruses are single-stranded DNA viruses that infect many plant species and cause serious losses in agronomically important crops. An earlier study showed that the Arabidopsis thaliana ecotype Pla-1 is resistant to infection by diverse geminivirus species and mapped the major resistance locus Geminivirus Resistance of Pla-1 1 (GRP1) to chromosome 1. In this study, we fine-mapped the GRP1 locus to a 0.6-Mb region and showed that its strength is gene-dosage-dependent. We also uncovered two minor resistance loci, GRP2 and GRP3, that mapped to chromosomes 3 and 5, respectively, and showed that GRP3 resistance is dependent on GRP1. RNA-Seq analysis of plants inoculated with the geminivirus, cabbage leaf curl virus (CaLCuV, Begomovirus brassicae), showed that AT1G31540, which is located in

SUBMITTER: Shen W 

PROVIDER: S-EPMC12680929 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature