Lotusin A: a novel pyrrole terpenoid hydrid from lotus roots (<i>Nelumbo nucifera</i> Gaertn.).

ABSTRACT: Nelumbo nucifera Gaertn. has been used as a traditional medicine and food. To date, many unknown constituents have been discovered. Most of the researches on secondary metabolites and their pharmacological properties focus on alkaloid derivatives. In this study, a novel pyrrole terpenoid hydrid, lotusin A (1), and five reported substances, cholestanol (2), stigmast-4-en-3-one (3), quercetin (4), isorhamnetin (5), and norartocarpetin (6), were isolated from the methanol extract of the roots of N. nucifera Gaertn. The structures (1-6) were identified via spectroscopic analyses of NMR (1D and 2D), HR-ESIMS, and comparisons with those previously reported in the literature. Compound 1, a pyrrole terpenoid hydrid, is a unique isolate from plant natural products. Compounds 1

SUBMITTER: Tran LVH 

PROVIDER: S-EPMC12705226 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature