Association of layer-specific knee cartilage T2-relaxation measurements with age, sex and cartilage morphology at 1.5-T MRI.

ABSTRACT:

Objective

This study aimed to establish normal knee cartilage T2-values at 1.5-Tesla, assess the influence of age and sex on T2-values, and compares T2-times between subjects with and without morphological cartilage changes.

Materials and methods

A sagittal 2D T2-weighted multi-slice multi-echo sequence (MSME) sequence with automatic generation of a color-coded T2-map was acquired at 1.5-Tesla in 929 volunteers (ages 28-89) from the Study-of-Health-in-Pomerania TREND-1 cohort. Knee morphology was assessed with the modified Noyes Score in eight cartilage regions. T2 measurements were performed manually in seven cartilage regions, including superficial and deep cartilage layers.

Results

Subjects with normal cartilage morphology (300 subjects) showed significant T2-value

SUBMITTER: Aschauer K 

PROVIDER: S-EPMC12711982 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature