Ontology highlight
ABSTRACT:
SUBMITTER: Helmer P
PROVIDER: S-EPMC12804329 | biostudies-literature | 2026 Jan
REPOSITORIES: biostudies-literature

Die Anaesthesiologie 20260107 1
Post-dural puncture headache (PDPH) is a frequent yet often underestimated complication of neuraxial anesthesia. The presumed mechanism involves cerebrospinal fluid loss due to accidental dural perforation, leading to intracranial hypotension and a secondary compensatory vasodilation. Meningeal irritation and neuroinflammatory processes also contribute to the complex pathophysiology. The main symptom is a severe orthostatic headache with pain exacerbation in an upright posture. This can be accom ...[more]