Steaming duration-dependent effects on the <i>in vivo</i> distribution, anti-fatigue activity, and gut microbiota modulation of <i>Polygonatum cyrtonema</i> Hua polysaccharides.

ABSTRACT:

Background

Polygonatum cyrtonema Hua is a traditional medicinal plant widely used for its anti-fatigue properties, with its polysaccharides (PCPs) believed to play a key role in these effects. Steaming, a necessary step before consumption, can alter the structure of PCPs. However, the impact of steaming-induced structural changes on their anti-fatigue activity remains unexplored. This study aims to investigate how different steaming durations affect the distribution, anti-fatigue activity, and modulation of gut microbiota by PCPs.

Methods

P. cyrtonema rhizomes were steamed for 0, 4, 8, and 12 h, and the polysaccharides were extracted. In vivo distribution was evaluated by conjugating PCPs with fluorescein isothiocyanate (FITC) for optical imaging. Anti-f

SUBMITTER: Lin S 

PROVIDER: S-EPMC12819684 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature