Outcomes of KDIGO-Defined CKD in U.S. Veterans With HFpEF, HFmrEF, and HFrEF.

ABSTRACT:

Background

Chronic kidney disease (CKD) is defined by the KDIGO (Kidney Disease: Improving Global Outcomes) guideline as abnormal kidney structure or function, present for >3 months, with implications for health. KDIGO-defined CKD is associated with poor outcomes in patients with heart failure (HF). Less is known about whether these associations vary by left ventricular ejection fraction.

Objectives

This study aims to determine the prevalence and outcomes of KDIGO-defined CKD in heart failure with preserved ejection fraction (HFpEF), heart failure with mildly reduced ejection fraction (HFmrEF), and heart failure with reduced ejection fraction (HFrEF).

Methods

Of the 1,446,053 veterans with an HF diagnosis (1991-2017) in the national Veterans Affairs electronic health

SUBMITTER: Patel S 

PROVIDER: S-EPMC12844147 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature