Transitions in frailty states and associated factors: a multistate analysis of the Italian Longitudinal Study on Aging population-based cohort.

ABSTRACT:

Background

Frailty is recognized as a dynamic and potentially reversible process, but comprehensive studies on its progression/regression are rare.

Objective

To investigate the frequency and characteristics of frailty transitions over time in a representative sample of older Italians.

Design and participants

As secondary analysis of the Italian Longitudinal Study on Aging (ILSA) population-based cohort, we studied all participants (n = 1339; women 47.5 %, age 72.7 ± 5.1) with complete information on changes in frailty status (or death) between consecutive ILSA surveys (T0, T1, T2).

Measurements

Frailty was operationalized according to Fried phenotype, analysing transitions between frailty, or death, during T0-T1, T1-T2 (4-, 5-year length). Transition probabilit

SUBMITTER: Galluzzo L 

PROVIDER: S-EPMC12856321 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature