Contralateral recurrent upper-tract urothelial carcinoma after curative surgery: a multicentre retrospective cohort study.

ABSTRACT:

Background

Contralateral recurrence of upper-tract urothelial carcinoma (UTUC) presents a clinical challenge, with limited evidence regarding optimal surgical management.

Objective

To compare oncological outcomes among patients with contralateral UTUC recurrence managed by second nephroureterectomy (NUR) or nephron-sparing surgery (NSS), relative to those undergoing primary NUR.

Design

A multicentre retrospective cohort study.

Methods

In this multicentre retrospective cohort, 3159 patients diagnosed with UTUC between 2018 and 2024 in the Taiwanese UTUC Registry were analysed. Patients undergoing curative-intent surgery were grouped as follows: unilateral UTUC treated with primary NUR; contralateral recurrence treated with a second NUR; and contralateral recurre

SUBMITTER: Kao YL 

PROVIDER: S-EPMC12901921 | biostudies-literature | 2026 Jan-Dec

REPOSITORIES: biostudies-literature