<i>Streptococcus pneumoniae</i> nasopharyngeal carriage in Vietnamese children during the first five years of life: a post hoc analysis.

ABSTRACT:

Background

Streptococcus pneumoniae (the pneumococcus) is one of the main causes of childhood mortality. Understanding pneumococcal serotype and lineage distribution in children is important for vaccine decision-making. We undertook a secondary analysis of nasopharyngeal swabs collected from unvaccinated children as part of pneumococcal vaccine studies to provide a comprehensive picture of pneumococcal carriage epidemiology in Vietnamese children during the first 60 months of life.

Methods

We analysed 4375 nasopharyngeal swabs from unvaccinated children to assess overall and vaccine-type pneumococcal carriage at 6, 12, 18, 24, and 60 months of age. For the latter three age groups, serotype distribution and genetic lineages (Global Pneumococcal Sequence Cluster, GPSCs)

SUBMITTER: Marincek F 

PROVIDER: S-EPMC12906029 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature