PDA: Pooled DNA analyzer.

ABSTRACT:

Background

Association mapping using abundant single nucleotide polymorphisms is a powerful tool for identifying disease susceptibility genes for complex traits and exploring possible genetic diversity. Genotyping large numbers of SNPs individually is performed routinely but is cost prohibitive for large-scale genetic studies. DNA pooling is a reliable and cost-saving alternative genotyping method. However, no software has been developed for complete pooled-DNA analyses, including data standardization, allele frequency estimation, and single/multipoint DNA pooling association tests. This motivated the development of the software, 'PDA' (Pooled DNA Analyzer), to analyze pooled DNA data.

Results

We develop the software, PDA, for the analysis of pooled-DNA data. PDA is original

SUBMITTER: Yang HC 

PROVIDER: S-EPMC1539032 | biostudies-literature | 2006 Apr

REPOSITORIES: biostudies-literature