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The spatial scale of genetic differentiation in a model organism: the wild yeast Saccharomyces paradoxus.


ABSTRACT: Little information is presently available on the factors promoting genetic divergence in eukaryotic microbes. We studied the spatial distribution of genetic variation in Saccharomyces paradoxus, the wild relative of Saccharomyces cerevisiae, from the scale of a few centimetres on individual oak trees to thousands of kilometers across different continents. Genealogical analysis of six loci shows that isolates from Europe form a single recombining population, and within this population genetic differentiation increases with physical distance. Between different continents, strains are more divergent and genealogically independent, indicating well-differentiated lineages that may be in the process of speciation. Such replicated populations will be useful for studies in population genomics.

SUBMITTER: Koufopanou V 

PROVIDER: S-EPMC1764930 | biostudies-literature | 2006 Nov

REPOSITORIES: biostudies-literature

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The spatial scale of genetic differentiation in a model organism: the wild yeast Saccharomyces paradoxus.

Koufopanou Vassiliki V   Hughes Joseph J   Bell Graham G   Burt Austin A  

Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20061101 1475


Little information is presently available on the factors promoting genetic divergence in eukaryotic microbes. We studied the spatial distribution of genetic variation in Saccharomyces paradoxus, the wild relative of Saccharomyces cerevisiae, from the scale of a few centimetres on individual oak trees to thousands of kilometers across different continents. Genealogical analysis of six loci shows that isolates from Europe form a single recombining population, and within this population genetic dif  ...[more]

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