Objectively monitored patching regimens for treatment of amblyopia: randomised trial.

ABSTRACT:

Objectives

To compare visual outcome in response to two prescribed rates of occlusion (six hours a day and 12 hours a day).

Design

Unmasked randomised trial.

Setting

Research clinics in two London hospitals.

Participants

97 children with a confirmed diagnosis of amblyopia associated with strabismus, anisometropia, or both.

Interventions

18 week period of wearing glasses (refractive adaptation) followed by occlusion prescribed ("patching") for six or 12 hours a day.

Main outcome measures

Visual acuity measured by logMAR letter recognition; objectively monitored rate of occlusion (hours a day).

Results

The mean age of children at study entry was 5.6 (SD 1.5) years. Ninety were eligible for occlusion but 10 dropped out in this phase, leaving 8

SUBMITTER: Stewart CE 

PROVIDER: S-EPMC2001048 | biostudies-literature | 2007 Oct

REPOSITORIES: biostudies-literature