Ontology highlight
ABSTRACT:
SUBMITTER: Yao JG
PROVIDER: S-EPMC2702218 | biostudies-literature | 2008 Mar
REPOSITORIES: biostudies-literature
Developmental biology 20080104 2
In eye development the tasks of tissue specification and cell proliferation are regulated, in part, by the Pax6 and Pax6(5a) proteins respectively. In vertebrates, Pax6(5a) is generated as an alternately spliced isoform of Pax6. This stands in contrast to the fruit fly, Drosophila melanogaster, which has two Pax6(5a) homologs that are encoded by the eyegone and twin of eyegone genes. In this report we set out to determine the respective contributions that each gene makes to the development of th ...[more]