Citalopram for continuation therapy after repetitive transcranial magnetic stimulation in vascular depression.

ABSTRACT:

Objectives

The authors previously reported that repetitive transcranial magnetic stimulation (rTMS) produced a response rate of 39.4% among 62 patients with treatment resistant vascular depression. This study was undertaken to assess the outcome of continuation therapy to prevent relapse among these patients during 9 weeks after completion of rTMS.

Design

Patients were randomly assigned to 18,000 pulses of rTMS given over 3 weeks or sham treatment using double blind methods. After rTMS, all patients were given 20 mg/day of citalopram for 9 weeks and reevaluated at 3, 6, and 9 weeks.

Setting

Outpatient continuation treatment trial.

Participants

Patients with vascular depression (N = 62), as determined by magnetic resonance imaging hyperintensities and three or m

SUBMITTER: Robinson RG 

PROVIDER: S-EPMC2758492 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature