Ontology highlight
ABSTRACT:
SUBMITTER: Sanchez J
PROVIDER: S-EPMC2919146 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
The Journal of biological chemistry 20100618 33
The Spalt-like family of zinc finger transcription factors is conserved throughout evolution and is involved in fundamental processes during development and during embryonic stem cell maintenance. Although human SALL1 is modified by SUMO-1 in vitro, it is not known whether this post-translational modification plays a role in regulating the activity of this family of transcription factors. Here, we show that the Drosophila Spalt transcription factors are modified by sumoylation. This modification ...[more]