Premorbid cognitive leisure independently contributes to cognitive reserve in multiple sclerosis.

ABSTRACT:

Objective

Consistent with the cognitive reserve hypothesis, higher education and vocabulary help persons with Alzheimer disease (AD) and multiple sclerosis (MS) better withstand neuropathology before developing cognitive impairment. Also, premorbid cognitive leisure (e.g., reading, hobbies) is an independent source of cognitive reserve for elders with AD, but there is no research on the contribution of leisure activity to cognition in MS. We investigated whether premorbid cognitive leisure protects patients with MS from cognitive impairment.

Methods

Premorbid cognitive leisure was surveyed in 36 patients with MS. Neurologic disease severity was estimated with brain atrophy, measured as third ventricle width on high-resolution MRI. Cognitive status was measured with a composi

SUBMITTER: Sumowski JF 

PROVIDER: S-EPMC3039206 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature