2-[6,8-Dibromo-3-(4-hy-droxy-cyclo-hex-yl)-1,2,3,4-tetra-hydro-quinazolin-2-yl]phenol methanol 0.25-solvate.

ABSTRACT: The title compound, C(20)H(22)Br(2)N(2)O(2)·0.25CH(4)O, was synthesized by the condensation reaction of salicyl-aldehyde with 4-(2-amino-3,5-dibromo-benzyl-amino)-cyclo-hexa-nol in methanol. There are four independent main mol-ecules and two half-occupied methanol solvent mol-ecules in the asymmetric unit. The dihedral angles between the two benzene rings in the four mol-ecules are 87.8 (6), 86.6 (6), 89.3 (6) and 83.1 (6)°. Each mol-ecule features an intra-molecular O-H⋯N hydrogen bond and a short N-H⋯Br link. In the crystal components are linked by O-H⋯O hydrogen bonds.

SUBMITTER: Wang ZG 

PROVIDER: S-EPMC3099869 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature